Partners

Gellight is a multidisciplinary project joining together 4 academic teams working in collaboration with a French SME. Expertises span from organic synthesis, photochemistry, physics to biology

IMRCP

IMRCP (Molecular Interactions and Chemical and Photochemical reactivities) laboratory is a mixed CNRS – Toulouse University research unit, specialized on soft matter. The IDeAS team (Dynamical Interfaces and Stimuli-responsive assemblies) working on GELLIGHT project focuses on the design and characterization of smart materials based on self-assembled or nanostructured systems.

IMRCP develops the synthesis of the photo-reactive hydrogel.

Team

  • Anne-Françoise Mingotaud GELLIGHT project leader.
  • Nancy Lauth de Viguerie
  • Véronique Pimienta
  • Clément Roux
  • Christophe Coudret
  • Juliette Fitremann
  • Camille Courtine

Webpage

www.imrcp.ups-tlse.fr

Itav

3D imaging R&D: Expertise in microscopy, multidimensional live imaging, image processing and analysis. Role in the project, specifications, cytotoxicity, microscopy tests, mechanical properties by AFM.

The ITAV is a Joint Service and Research Unit CNRS – Université Toulouse III Paul Sabatier. It is a cross-disciplinary center for biological research, dedicated to innovation in the fields of Bio-Nano-Info-Technologies, encouraging cross-disciplinary projects in the life sciences which are chosen for their potential for application: biomathematics, bioinformatics, modeling, in vivo imaging, chemistry/biology interface, biomedical instrumentation and robotics. The 3D imaging R&D activity aims at developing new 3D imaging technologies based on the SPIM/LSFM (Light Sheet Fluorescence Microscopy) combining innovative adaptive optics and photomanipulation devices in the optical path, and innovative and versatile sample holders.

Team

  • Corinne Lorenzo (P.I.)
  • Jacques Rouquette (microscopy specialist, CNRS)
  • Javier Morgado (microscopy optics, UPS)
  • Childerick Séverac (AFM specialist, CNRS)

Webpage

http://www.itav.fr/index.php/en/

I2MC

“ Molecular and clinical determinants of the cardiac architecture”

The global research program of the I2MC team relies on understanding the relationship between the architecture of the cardiac tissue (more specifically of the cardiac contractile cells, i.e, the cardiomyocytes-CM) and the function and pharmacology of the heart.

For that purpose, these last years, the team acquired specific skills in high-resolution imaging of the cardiac tissue & cells (AFM/MET). One original result arising from this work was: 1/ the identification of a crest motif at the surface of the CMs establishing CM-CM lateral contacts in the cardiac tissue and 2/ its modulation in different physio-pathophysiological contexts.

Team

  • Céline Galès (P.I.)

Webpage

http://www.i2mc.inserm.fr/index.php/en/

IMMM

Institut des Molécules et Matériaux du Mans (IMMM). IMMM is mixed CNRS/Le Mans University research unit divided in four research axes:  organic synthesis, inorganic materials, physics of confined matter and chemistry/physical chemistry of polymers.

The Polymers, Colloids, Interfaces (PCI) team working on GELLIGHT project focuses on the study of physical chemical properties of light-responsive hydrogels by light scattering and rheometry.

Team

  • Erwan NICOL (Ass. Prof.  Le Mans University, photo-polymerizable hydrogels)

Webpage

http://immm.univ-lemans.fr/fr/index.html
Specific Polymers logo

Specific Polymers

SPECIFIC POLYMERS (2003, Castries, FRANCE) is a SME with 18 employees acting as R&D service provider and scale up producer in the field of functional monomers & polymers with high specificity.

The main goal of the innovative products developed by SPECIFIC POLYMERS is to validate proof of concepts in close collaboration with its customers (academic laboratories and R&D departments of high tech industrial groups). In almost 15 years, SPECIFIC POLYMERS developed the synthesis of more than 10 000 functional building blocks, monomers and polymers, and is now working with more than 500 customers and partners in more than 50 countries worldwide. Products provided by SPECIFIC POLYMERS are used for a very wide range of applications such as surface finishing (glass, metal, nanoparticles), construction industry, aeronautic, automotive (paint, tyres, sealants), pharmaceutical industry, cosmetics, optoelectronic, water treatment and energy (fuel cells, solar cells or lithium batteries).

Team

  • Camille Chatard (Polymer synthesis)

Webpage

www.specificpolymers.fr

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Gellight Project

Project

Responses of biological tissues to mechanical stress are increasingly assessed, owing to their demonstrated link to many biological functions and the onset and progression of various pathologies such as fibrosis or ischemia. …

Partners

Gellight is a multidisciplinary project joining together 4 academic teams working in collaboration with a French SME. …

Latest publications

Process simulation

Full characterization of photoresponsive inclusion complexes

Quantitative kinetic modeling in photoresponsive supralolecular chemistry: the case of water-soluble azobenzene

J. Org. Chem. (2020) 85(10) 6509-6518 doi.org/10.1021/acs.joc.0c00461

Thanks to Lab2screen for the TOC design

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Light sheet microscope image

Adaptive Light-Sheet Fluorescence Microscopy

Highly Sensitive Shack–Hartmann Wavefront Sensor: Application to Non-Transparent Tissue Mimic Imaging with Adaptive Light-Sheet Fluorescence Microscopy

Methods Protoc. 2019, 2(3), 59

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