Camille’s PhD defense February 2022, 10th

Camille presented her PhD work during her defense in front of a jury including Pr Catherine Amiel (ICPEM Thiais), Dr Morgan Delarue (LAAS-CNRS, Toulouse), Pr Jean-Serge Remy (Univ. Strasbourg) and Dr Yvette Tran (ESPCI, Paris).

Her presentation was entitled: Macro- and supramolecular hydrogels photocontrollable in the visible range

Her work spanned from the characterization of the association between azobenzenes bearing halides atoms and b-cyclodextrin to the synthesis and the characterization of the hydrogels. The results have shown that hydrogels with mechanical properties compatible with different biological tissues were accessible and biocompatible.

Congratulations Camille!

Inès at the European Researchers Night event

On September 24th, Inès participated to the European Researchers Night in Le Mans, an event organized throughout Europe to share the passion of science with the public.

She presented the topic “hydrogel and health” and had in her researcher’s luggage some useful tools to explain her work: a sponge, some scoubidous, some slime, a dentist irradiation lamp and a loupe!

She also participated to a speed-searching session and gave an interview to the radio.

Find out more about Inès in the researchers’ portrait section.

Presentation at ESPS 2021

Watch Anne-Françoise’s presentation at the European Symposium on Photopolymer Sciences which took place online in June 2021

Presentation at SupraBio 2021

Watch Nancy’s presentation at the International Symposium on SupraBiomolecular Systems which took place online in May 2021.

New recruitments

Inès Hamouda and Divyendu Valappil are joining us starting February 15th.
Inès is a post-doc and she will work at IMMM in Le Mans to characterize the hydrogels by rheology and Light Scattering.
Divyendu is a research engineer and she will develop the SPIM environment at Restore laboratory.

Gellight explained to the kids!

An article about Gellight has just been published on CurioKids, a website dedicated to the kids and which makes science fun and understandable to all.
Thanks to Laetitia Mespouille for this highlight!

To read this article

Camille’s first oral communication

On October 2020, Camille Courtine attended NICE-2020 International Conference, which is organized with the objective to share new developments in the growing field of bioinspired chemistry and materials.

Camille presented a part of her PhD work:
“Photo-switchable azobenzene-cyclodextrin complexes in water: a tool to mimic extra cellular matrix”

Gellight Project

Project

Responses of biological tissues to mechanical stress are increasingly assessed, owing to their demonstrated link to many biological functions and the onset and progression of various pathologies such as fibrosis or ischemia.

© N. Kebalo

The study of these phenomena implies the need of new technologies enabling concomitant stimulation and characterization of the tissue. Materials that can be tuned by an external stimulus have been thus increasingly assessed for applications linked to biology. Among them, stimuli-responsive hydrogels are essential, owing to their naturally high content of water.

In this topic, the GELLIGHT project aims at developing biocompatible hydrogels, the stiffness of which can be reversibly tuned by light and which will be used as active sample holders for photonic microscopy of 3D-cultured cardiac cells. For this, dual chemical and reversible physical (based on host-guest interactions) crosslinking will be used and the biological tissue encapsulated directly inside the hydrogels.

This project will lead to the development of new visible-responsive hydrogel formulations, which will open applications for soft actuators for biology or responsive drug delivery systems. It will also provide new tools to simultaneously manipulate and observe biological tissue. This is expected to constitute a basis for next generation mechanobiology set-ups with a diversification of the studied pathologies.